Introduction
When it comes to hyaluronic acid (HA), do you consider it just an ingredient in skincare products? We all know that H.A. Hyaluronan has 10 proven benefits. Let’s explore them together.
Before we discuss the 10 benefits of hyaluronan, let’s take a closer look at hyaluronic acid. What are the characteristics?
What is Hyaluronic Acid?
Hyaluronic acid is transparent and sticky. They are found in our skin, connective tissue, and in our eyes.
Table 1. HA content in different tissues of the human body
| Tissue | Hyaluronic Acid Content (mg/g) |
| Vitreous Body | 140～340 |
| Umbilical Cord | 4100 |
| Synovial Fluid | 1400～3600 |
| Dermis | 200～500 |
| Epidermis | 100 |
| Thoracic Lymph Fluid | 0.2～50 |
| Urine | 0.1～0.3 |
| Serum | 0.01～0.1 |
hyaluronic acid content in different tissues of the human body
Hyaluronan is highly hydrophilic, so it is often used as a solvent in cosmetics.
At the same time, it also has a viscous fluid and is an important component of synovial fluid.
Of course, these are just the tip of the iceberg of hyaluronic acid knowledge. Let’s take a closer look at the top 10 benefits of hyaluronan.
10 Proven Benefits of Hyaluronic Acid
1. Hyaluronic acid moisturizes the skin
One well-known benefit of hyaluronic acid is its moisturizing properties. Hyaluronic acid is a powerful ingredient in skin care. This is because it can pull 1,000 times its own weight in water. Hyaluronic acid absorbs moisture from the environment and binds to the skin.
As a result, HA enhances the skin’s ability to retain moisture, making it plump and youthful.
In addition, HA can reduce the appearance of fine lines and wrinkles on the skin. For those with dry or dehydrated skin, hyaluronan can provide vital skin moisture to help restore the skin’s natural barrier, leaving skin smooth and radiant
2. Hyaluronic acid repairs scar tissue
Acne scars are a chronic concern for many people, often causing uneven skin tone. An effective treatment for wrinkles is hyaluronic acid. It plays an important role in the repair and regeneration of skin tissue. Hyaluronan can stimulate collagen synthesis, which can improve skin structure, fill scars and even out skin.
In addition, its moisturizing properties can prevent inflammation and redness associated with acne. Over time, the skin will become even and smooth.
3. Hyaluronic acid promotes wound healing
The body naturally increases HA levels in damaged areas, emphasizing its importance in the healing process. Hyaluronan helps wound healing by controlling the amount of inflammation and signaling the body to produce more blood vessels in the damaged area. Its moisturizing properties also moisturize and create an ideal environment for healing, which is important for root repair. Studies have shown that HA.
Fig 1. How Hyaluronic Acid Repairs Wounds
4. Hyaluronic Acid reduces joint pain
In the joints, Hyaluronic Acid acts as a lubricant and shock absorber, which is important for maintaining joint health and function. This is especially beneficial for individuals with osteoporosis, which causes joint cartilage damage. HA injections, known as viscous fillers, can help reduce pain and increase joint elasticity and restorative elasticity. These reduced friction and cushioning effects reduce joint pain greater and improves overall joint function.
Fig 2. Anatomy of the healthy and osteoarthritic knee joint[i]
5. Hyaluronic acid effectively prevents dry eyes
Symptoms of dry eye usually occur where the eye does not drain enough or the tears evaporate too quickly. Hyaluronic acid is commonly used in eye drops and artificial tears because of its excellent moisture retention properties. It helps lubricate the eyes and prevents them from becoming dry, irritated and uncomfortable. In addition, HA promotes scar healing on the ocular surface and reduces inflammation, effectively treating eye conditions
6. Hyaluronic acid prevents adhesion after surgery
Hyaluronic acid has been shown to reduce this adhesion, which is scar tissue that forms between internal organs and tissues after surgery and can lead to postoperative complications and chronic pain. It is used in surgical procedures in gel or solution form to help separate tissues during treatment. By providing a protective barrier, HA reduces muscle stiffness and aids in faster recovery.
7. Hyaluronic acid acts as a drug carrier
In pharmaceuticals, hyaluronic acid’s biocompatibility and ability to enhance drug delivery make it an effective drug. HA can encapsulate drugs, ensure targeted delivery to specific tissues or organs, improving drug efficacy and reducing side effects. Use in drug delivery systems of the drug is especially useful for therapies that require specific targeting, such as cancer treatment, where HA can help localize the drug to a tumor
8. Hyaluronic acid soothes the symptoms of acid reflux
Gastroesophageal reflux disease (GERD) is a condition in which too much stomach acid is refluxed into the food chain, causing irritation. Hyaluronic Acid can help soothe and repair damaged esophageal lining. Studies have shown that HA. This helps reduce acid reflux symptoms and supports overall digestive health.
9. Hyaluronic acid maintains bone density
Bone health is another area where Hyaluronic Acid shows promise. HA is involved in bone formation and repair, contributing to bone density and density. It increases the activity of osteoblasts, the cells that promote bone growth, and helps in the formation of new bone tissue. By supporting these properties, HA can help prevent and treat osteoporosis and other bone-related conditions, as well as maintain bone density and elasticity
10. Hyaluronic acid is an antioxidant
Hyaluronic acid also exhibits antioxidant properties, helping to protect the skin and other tissues from oxidative damage caused by free radicals. Free radicals are unstable molecules that can damage cells, leading to premature aging and various diseases. HA’s ability to neutralize these harmful molecules helps reduce inflammation and support cell health. This antioxidant properties are particularly beneficial for the skin, where it helps maintain a youthful appearance and prevents damage from environmental stressors such as UV rays and pollution
Conclusion
In conclusion, Hyaluronic Acid offers a multitude of benefits that extend beyond simple hydration. Its roles in skin repair, wound healing, joint health, eye care, and more highlight its versatility and importance in both medical and cosmetic applications. By understanding and utilizing the diverse properties of HA, individuals can enhance their overall health and well-being, benefiting from this remarkable natural substance.
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Medical Grade Hyaluronic Acid and Wound Healing
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[i] Fig 1. Anatomy of the healthy and osteoarthritic knee joint. Created via canvas. Source: Smith, Abbi & Sigurbjörnsdóttir. (2022). Hedgehog signaling in bone and osteoarthritis: the role of Smoothened and cholesterol. The FEBS Journal. 290. 10.1111/febs.16440.